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Обрубов А.С., Обрубов С.А.
Офтальмологические проявления фармакотерапии: заместительная гормональная терапия у женщин
Российский национальный исследовательский медицинский университет им. Н.И. Пирогова Минздрава России
1. Гинекология: национальное руководство / Под ред. В.И. Кулакова, Г.М. Савельевой, И.Б. Манухина.— М.: ГЭОТАР-Медиа, 2007.— С. 462-477.
2. Краснов М.Л., Марголис М.Г. Гормональная терапия при глазных заболеваниях.— М.: Медицина, 1970.— С. 99–104.
3. Нефедова Д.М. Особенности синдрома «сухого глаза» на фоне приема гормональных препаратов // Офтальмологические ведомости.— 2008.— Т. 1, №1.— С. 87-90.
4. Aina F.O., Smeeth L., Hubbard R. et al. Hormone replacement therapy and cataract: a population-based case-control study // Eye.— 2006.— Vol. 20.— P. 417-422.
5. Barnes J.F., Farish E., Rankin M., Hart D.M. Effects of two continuous hormone therapy regimens on C-reactive protein and homocysteine // Menopause.— 2005.— Vol. 12.— P. 92-98.
6. Battaglia C., Mancini F., Regnani G. et al. Hormone therapy and ophthalmic artery blood flow changes in women with primary open-angle glaucoma // Menopause.— 2004.— Vol. 11.— P. 69-77.
7. Bigsby R.M., Cardenas H., Caperell-Grant A., Grubbs C.J. Protective effects of estrogen in a rat model of age-related cataracts // Proc. Natl. Acad. Sci. USA.— 1999.— Vol. 96.— P. 9328-9332.
8. Bourassa P.-A., Milos P.M., Gaynor B.J. et al. Estrogen reduces atherosclerotic lesion development in apolipoprotein E-deficient mice // Proc. Natl. Acad. Sci. USA.— 1996.— Vol. 93.— P. 10022-10027.
9. Cavaney-Brooker D.M., Rakoczy P.E. Cloning of a major human retinal pigment epithelial lysosomal aspartic protease and mapping its transcriptional start sites // Curr. Eye Res.— 1999.— Vol. 18.— P. 310-318.
10. Cirigliano M. Bioidentical hormone therapy: a review of the evidence // J. Women’s Health.— 2007.— Vol. 16 (5).— P. 600-631.
11. Cousins S.W., Marin-Castano M.E., Espinosa-Heidmann D.G. et al. Female gender, estrogen loss, and Sub-RPE deposit formation in aged mice // Invest. Ophthalmol. Vis. Sci.— 2003.— Mar.— Vol. 44 (3).— P. 1221-1229.
12. Cumming R.G., Mitchell P. Hormone replacement therapy, reproductive factors, and cataract: the Blue Mountains Eye Study // Am. J. Epidemiol.— 1997.— Vol. 145.— P. 242-249.
13. Davis V.L., Chan C.-C., Schoen T.J. et al. An estrogen receptor repressor induces cataract formation in transgenic mice // Proc. Natl. Acad. Sci. USA.— 2002.— Vol. 99.— № 14.— P. 9427-9432.
14. Deschenes M.C., Descovich D., Moreau M. et al. Postmenopausal Hormone Therapy Increases Retinal Blood Flow and Protects the Retinal Nerve Fiber Layer // Invest. Ophthalmol. Vis. Sci.— 2010.— Vol. 51.— P. 2587-2600.
15. Dubey R.K., Jackson E.K., Gillespie D.G. et al. Clinically used estrogens differentially inhibit human aortic smooth muscle cell growth and mitogen-activated protein kinase activity // Arterioscler. Thromb. Vasc. Biol.— 2000.— Vol. 20.— P. 964-972.
16. Esmaeli B., Harvey J.T., Hewlett B. Immunohistochemical evidence for estrogen receptors in meibomian glands // Ophthalmology.— 2000.— Vol. 107.— P. 180-184.
17. Evans V., Millar T.J., Eden J. A., Willcox M.D. Menopause, hormone replacement therapy and tear function // Adv. Exp. Med. Biol.— 2002.— Vol. 506.— P. 1029-1033.
18. Fraser-Bell S., Wu J., Klein R. et al. Smoking, alcohol intake, estrogen use, and age-related macular degeneration in Latinos: the Los Angeles Latino Eye Study // Am. J. Ophthalmol.— 2006,.— Jan.— Vol. 141 (1).— P. 79-87.
19. Freeman E.E., Munoz B., Bressler S.B., West S.K. Hormone replacement therapy, reproductive factors, and age-related macular degeneration: the Salisbury Eye Evaluation Project // Ophthalmic Epidemiol.— 2005.— Vol. 12.— P. 37-45.
20. Freeman E.E., Munoz B., Schein O.D., West S.K. Hormone replacement therapy and lens opacities: the Salisbury Eye Evaluation project // Arch. Ophthalmol.— 2001.— Vol. 119.— P. 1687-1692.
21. Friedman E. The role of the atherosclerotic process in the pathogenesis of agerelated macular degeneration // Am. J. Ophthalmol.— 2000.— Vol. 130(5).— P. 658-663.
22. Fuchsjager-Mayrl G., Nepp J., Schneeberger C. et al. Identification of estrogen and progesterone receptor mRNA expression in the conjunctiva of premenopausal women // Invest. Ophthalmol. Vis. Sci.— 2004.— Vol. 43.— P. 2841-2844.
23. Gligorijevic J., Krstic M., Babic G. Immunohistochemical detection of estrogen and progesterone receptors in the human lacrimal gland // Arch. Biol. Sci.— Belgrade.— 2011.— Vol. 63, N 2.— P. 319-324.
24. Haan M.N., Klein R., Klein B.E. et al. Hormone Therapy and Age-Related Macular Degeneration: The Women’s Health Initiative Sight Exam Study // Arch. Ophthalmol.— 2006.— Jul.— Vol. 124 (7).— P. 988-992.
25. Hales A.M., Chamberlain C.G., Murphy C.R., McAvoy J.W. Estrogen protects lenses against cataract induced by transforming growth factor-b (TGFb) // J. Exp. Med.— 1997.— Vol. 185.— P. 273-280.
26. Harris-Yitzhak M., Harris A., Ben-Refael Z. et al. Estrogenreplacement therapy: effects on retrobulbar hemodynamics // Am. J. Ophthalmol.— 2000.— Vol. 129.— P. 623-628.
27. Jensen A. A., Higginbotham E.J., Guzinski G.M. et al. A survey of ocular complaints in postmenopausal women // J. Assoc. Acad. Minor. Phys.— 2000.— Vol. 11 (2-3).— P. 44-49.
28. Kang J.H., Wiggs J.L., Haines J. et al. Reproductive factors and NOS3 variant interactions in primary openangle glaucoma // Molecular Vision.— 2011.— Vol. 17.— P. 2544-2551.
29. Klein B.E., Klein R., Jensen S.C., Ritter L.L. Are sex hormones associated with age-related maculopathy in women? The Beaver Dam Eye Study // Trans. Am. Ophthalmol. Soc.— 1994.— Vol. 92.— P. 289-297.
30. Klein B.E., Klein R., Lee K.E. Incidence of age-related cataract: the Beaver Dam Eye Study // Arch. Ophthalmol.— 1998.— Vol. 116.— 219-225.
31. Kuscu N.K., Toprak A.B., Vatansever S. et al. Tear function changes of postmenopausal women in response to hormone replacement therapy // Maturitas.— 2003.— Vol. 44.— P. 63-68.
32. Lee A.J., Mitchell P., Rochtchina E., Healey P.R. Female reproductive factors and open angle glaucoma: the Blue Mountains Eye Study // Br. J. Ophthalmol.— 2003.— Vol. 87.— P. 1324-1328.
33. Lira S.C., Jimenez A.M., Olhovich I.G. Cambios oculares posteriores a la administracion de tratamiento hormonal en mujeres posmenopausicas. Reporte preliminar // Ginecol. Obstet. Mex.— 2005.— Vol. 73.— P. 194-197.
34. Mabuchi F., Sakurada Y., Kashiwagi K. et al. Estrogen receptor beta gene polymorphism and intraocular pressure elevation in female patients with primary openangle glaucoma // Am. J. Ophthalmol.— 2010.— Vol. 149.— P. 826-830.
35. Makela S., Savolainen H., Aavik E. et al. Differentiation between vasculoprotective and uterotrophic effects of ligands with different binding affinities to estrogen receptors alpha and beta // Proc. Natl. Acad. Sci. USA.— 1999.— Vol. 96.— P. 7077-7082.
36. Munaut C., Lambert V., Noеl A. et al. Presence of oestrogen receptor type β in human retina // Br. J. Ophthalmol.— 2001.— Vol. 85.— P. 877-882.
37. Nathanson J.A., McKee M. Identification of an extensive system of nitrc oxide-producing cells in the ciliary muscle and outflow pathway of the human eye // Invest. Ophthalmol. Vis. Sci.— 1995.— Vol. 36.— P. 1765-1772.
38. Ogueta S.B., Schwartz S.D., Yamashita C.K., Farber D.B. Estrogen Receptor in the Human Eye: Influence of Gender and Age on Gene Expression // Invest. Opthalmol. Vis. Sci.— 1999.— Vol. 40.— Aug.— № 9.— P. 1906-1911.
39. Ozcura F., Dundar S.O., Cetin E.D. et al. Effect of estrogen replacement therapy on lens epithelial cell apoptosis in an experimental rat model // International ophthalmology.— 2010.— Vol. 30 (3).— P. 279-284.
40. Paech K., Webb P., Kuiper G.G. et al. Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites // Science.— 1997.— Vol. 277.— P. 1508-1510.
41. Pasquale L.R., Kang J.H. Female reproductive factors and primary open-angle glaucoma in the Nurses’ Health Study // Eye (Lond).— 2011.— Vol. 25.— P. 633-641.
42. Pelit A., Bagis T., Kayaselcuk F., et al. Tear function tests and conjunctival impression cytology before and after hormone replacement therapy in postmenopausal women // Eur. J. Ophthalmol.— 2003.— Vol. 13.— P. 337-342.
43. Prestwood K.M., Unson C., Kulldorff M., Cushman M. The effect of different doses of micronized 17β-estradiol on C-reactive protein, interleukin-6, and lipids in older women // J. Gerontol. A Biol. Sci. Med. Sci.— 2004.— Vol. 59.— P. 827-832.
44. Rakic J.-M., Lambert V., Deprez M. et al. Estrogens reduce the expression of YKL-40 in the retina: implications for eye and joint diseases // Invest Ophthalmol Vis Sci.— 2003.— Vol. 44 (4).— P. 1740-1746.
45. Rakoczy E.P., Zhang D., Lay M., Constable I. Accelerated rod outer segment (ROS) derived debris accumulation linked to the production of enzymatically inactive cathepsin D // Invest. Ophthalmol. Vis. Sci.— 2000.— Vol. 41.— Abstract 2190.
46. Schaumberg D.A., Buring J.E., Sullivan D.A., Dana M.R. Hormone replacement therapy and dry eye syndrome // JAMA.— 2001.— Vol. 286.— P. 2114-2119.
47. Scott G., Yiu S. C., Wasilewski D. et al. Combined esterified estrogen and methyltestosterone treatment for dry eye syndrome in postmenopausal woman // Am. J. Ophthalmol.— 2005.— Vol. 139, № 6.— P. 1109-1110.
48. Seitzman R.L., Mangione C., Ensrund K.E. et al. Postmenopausal hormone therapy and age-related maculopathy in older women // Ophthalmic Epidemiol.— 2008.— Vol. 15.— P. 308–316.
49. Siesky B.A., Harris A., Patel C. et al. Comparison of visual function and ocular hemodynamics between pre– and postmenopausal women // Eur. J. Ophthalmol.— 2008.— Vol. 18.— P. 320-323.
50. Spelsberg H., Klueppel M., Reinhard T. et al. Detection of Oestrogen receptors (ER) α and β in conjunctiva, lacrimal gland, and tarsal plates // Eye.— 2004.— Vol. 18.— P. 729-733.
51. Sullivan D.A. Androgen deficiency & dry eye syndromes // Arch. Soc. Esp. Oftalmol.— 2004.— Vol. 79.— P. 49-50.
52. Suzuki T., Kinoshita Y., Tachibana M. et al. Expression of sex steroid hormone receptors in human cornea // Curr. Eye Res.— 2001.— Vol. 22.— P. 28-33.
53. Tachibana M., Kasukabe T., Kobayashi Y. et al. Expression of estrogen receptor alpha and beta in the mouse cornea // Invest. Ophthalmol. Vis. Sci.— 2000.— Vol. 41.— P. 668-670.
54. Tint N.L., Alexander P., Tint K.M. et al. Hormone therapy and intraocular pressure in nonglaucomatous eyes // Menopause.— 2010.— Jan.-Feb.— Vol. 17 (1).— P. 157-160.
55. Uncu G., Avci R., Uncu Y. et al. The effects of different hormone replacement therapy regimens on tear function, intraocular pressure and lens opacity // Gynecol. Endocrinol.— 2006.— Vol. 22, N 9.— P. 501-505.
56. Vance D.A. Premarin: The Intriguing History of a Controversial Drug // International Journal of Pharmaceutical Compounding.— 2007.— Vol. 11 (4).— P. 282-287.
57. Wang C., Shi X., Chen X. et al. 17-β-estradiol inhibits hyperosmolarity-induced proinflammatory cytokine elevation via the p38 MAPK pathway in human corneal epithelial cells // Molecular Vision.— 2012.— Vol. 18.— P. 1115-1122.
58. Wang X., Simpkins J.W., Dykens J.A., Cammarata P.R. Oxidative damage to human lens epithelial cells in culture: Estrogen protection of mitochondrial potential, ATP, and cell viability // Invest. Ophthalmol. Vis. Sci. 2003.— Vol. 44, №5.— P. 2067-2075.
59. Wickham L. A., Gao J., Toda I. et al. Identification of androgen, estrogen and progesterone receptor mRNAs in the eye // Acta Ophthalmol. Scand.— 2000.— Vol. 78.— P. 146-153.
2. Краснов М.Л., Марголис М.Г. Гормональная терапия при глазных заболеваниях.— М.: Медицина, 1970.— С. 99–104.
3. Нефедова Д.М. Особенности синдрома «сухого глаза» на фоне приема гормональных препаратов // Офтальмологические ведомости.— 2008.— Т. 1, №1.— С. 87-90.
4. Aina F.O., Smeeth L., Hubbard R. et al. Hormone replacement therapy and cataract: a population-based case-control study // Eye.— 2006.— Vol. 20.— P. 417-422.
5. Barnes J.F., Farish E., Rankin M., Hart D.M. Effects of two continuous hormone therapy regimens on C-reactive protein and homocysteine // Menopause.— 2005.— Vol. 12.— P. 92-98.
6. Battaglia C., Mancini F., Regnani G. et al. Hormone therapy and ophthalmic artery blood flow changes in women with primary open-angle glaucoma // Menopause.— 2004.— Vol. 11.— P. 69-77.
7. Bigsby R.M., Cardenas H., Caperell-Grant A., Grubbs C.J. Protective effects of estrogen in a rat model of age-related cataracts // Proc. Natl. Acad. Sci. USA.— 1999.— Vol. 96.— P. 9328-9332.
8. Bourassa P.-A., Milos P.M., Gaynor B.J. et al. Estrogen reduces atherosclerotic lesion development in apolipoprotein E-deficient mice // Proc. Natl. Acad. Sci. USA.— 1996.— Vol. 93.— P. 10022-10027.
9. Cavaney-Brooker D.M., Rakoczy P.E. Cloning of a major human retinal pigment epithelial lysosomal aspartic protease and mapping its transcriptional start sites // Curr. Eye Res.— 1999.— Vol. 18.— P. 310-318.
10. Cirigliano M. Bioidentical hormone therapy: a review of the evidence // J. Women’s Health.— 2007.— Vol. 16 (5).— P. 600-631.
11. Cousins S.W., Marin-Castano M.E., Espinosa-Heidmann D.G. et al. Female gender, estrogen loss, and Sub-RPE deposit formation in aged mice // Invest. Ophthalmol. Vis. Sci.— 2003.— Mar.— Vol. 44 (3).— P. 1221-1229.
12. Cumming R.G., Mitchell P. Hormone replacement therapy, reproductive factors, and cataract: the Blue Mountains Eye Study // Am. J. Epidemiol.— 1997.— Vol. 145.— P. 242-249.
13. Davis V.L., Chan C.-C., Schoen T.J. et al. An estrogen receptor repressor induces cataract formation in transgenic mice // Proc. Natl. Acad. Sci. USA.— 2002.— Vol. 99.— № 14.— P. 9427-9432.
14. Deschenes M.C., Descovich D., Moreau M. et al. Postmenopausal Hormone Therapy Increases Retinal Blood Flow and Protects the Retinal Nerve Fiber Layer // Invest. Ophthalmol. Vis. Sci.— 2010.— Vol. 51.— P. 2587-2600.
15. Dubey R.K., Jackson E.K., Gillespie D.G. et al. Clinically used estrogens differentially inhibit human aortic smooth muscle cell growth and mitogen-activated protein kinase activity // Arterioscler. Thromb. Vasc. Biol.— 2000.— Vol. 20.— P. 964-972.
16. Esmaeli B., Harvey J.T., Hewlett B. Immunohistochemical evidence for estrogen receptors in meibomian glands // Ophthalmology.— 2000.— Vol. 107.— P. 180-184.
17. Evans V., Millar T.J., Eden J. A., Willcox M.D. Menopause, hormone replacement therapy and tear function // Adv. Exp. Med. Biol.— 2002.— Vol. 506.— P. 1029-1033.
18. Fraser-Bell S., Wu J., Klein R. et al. Smoking, alcohol intake, estrogen use, and age-related macular degeneration in Latinos: the Los Angeles Latino Eye Study // Am. J. Ophthalmol.— 2006,.— Jan.— Vol. 141 (1).— P. 79-87.
19. Freeman E.E., Munoz B., Bressler S.B., West S.K. Hormone replacement therapy, reproductive factors, and age-related macular degeneration: the Salisbury Eye Evaluation Project // Ophthalmic Epidemiol.— 2005.— Vol. 12.— P. 37-45.
20. Freeman E.E., Munoz B., Schein O.D., West S.K. Hormone replacement therapy and lens opacities: the Salisbury Eye Evaluation project // Arch. Ophthalmol.— 2001.— Vol. 119.— P. 1687-1692.
21. Friedman E. The role of the atherosclerotic process in the pathogenesis of agerelated macular degeneration // Am. J. Ophthalmol.— 2000.— Vol. 130(5).— P. 658-663.
22. Fuchsjager-Mayrl G., Nepp J., Schneeberger C. et al. Identification of estrogen and progesterone receptor mRNA expression in the conjunctiva of premenopausal women // Invest. Ophthalmol. Vis. Sci.— 2004.— Vol. 43.— P. 2841-2844.
23. Gligorijevic J., Krstic M., Babic G. Immunohistochemical detection of estrogen and progesterone receptors in the human lacrimal gland // Arch. Biol. Sci.— Belgrade.— 2011.— Vol. 63, N 2.— P. 319-324.
24. Haan M.N., Klein R., Klein B.E. et al. Hormone Therapy and Age-Related Macular Degeneration: The Women’s Health Initiative Sight Exam Study // Arch. Ophthalmol.— 2006.— Jul.— Vol. 124 (7).— P. 988-992.
25. Hales A.M., Chamberlain C.G., Murphy C.R., McAvoy J.W. Estrogen protects lenses against cataract induced by transforming growth factor-b (TGFb) // J. Exp. Med.— 1997.— Vol. 185.— P. 273-280.
26. Harris-Yitzhak M., Harris A., Ben-Refael Z. et al. Estrogenreplacement therapy: effects on retrobulbar hemodynamics // Am. J. Ophthalmol.— 2000.— Vol. 129.— P. 623-628.
27. Jensen A. A., Higginbotham E.J., Guzinski G.M. et al. A survey of ocular complaints in postmenopausal women // J. Assoc. Acad. Minor. Phys.— 2000.— Vol. 11 (2-3).— P. 44-49.
28. Kang J.H., Wiggs J.L., Haines J. et al. Reproductive factors and NOS3 variant interactions in primary openangle glaucoma // Molecular Vision.— 2011.— Vol. 17.— P. 2544-2551.
29. Klein B.E., Klein R., Jensen S.C., Ritter L.L. Are sex hormones associated with age-related maculopathy in women? The Beaver Dam Eye Study // Trans. Am. Ophthalmol. Soc.— 1994.— Vol. 92.— P. 289-297.
30. Klein B.E., Klein R., Lee K.E. Incidence of age-related cataract: the Beaver Dam Eye Study // Arch. Ophthalmol.— 1998.— Vol. 116.— 219-225.
31. Kuscu N.K., Toprak A.B., Vatansever S. et al. Tear function changes of postmenopausal women in response to hormone replacement therapy // Maturitas.— 2003.— Vol. 44.— P. 63-68.
32. Lee A.J., Mitchell P., Rochtchina E., Healey P.R. Female reproductive factors and open angle glaucoma: the Blue Mountains Eye Study // Br. J. Ophthalmol.— 2003.— Vol. 87.— P. 1324-1328.
33. Lira S.C., Jimenez A.M., Olhovich I.G. Cambios oculares posteriores a la administracion de tratamiento hormonal en mujeres posmenopausicas. Reporte preliminar // Ginecol. Obstet. Mex.— 2005.— Vol. 73.— P. 194-197.
34. Mabuchi F., Sakurada Y., Kashiwagi K. et al. Estrogen receptor beta gene polymorphism and intraocular pressure elevation in female patients with primary openangle glaucoma // Am. J. Ophthalmol.— 2010.— Vol. 149.— P. 826-830.
35. Makela S., Savolainen H., Aavik E. et al. Differentiation between vasculoprotective and uterotrophic effects of ligands with different binding affinities to estrogen receptors alpha and beta // Proc. Natl. Acad. Sci. USA.— 1999.— Vol. 96.— P. 7077-7082.
36. Munaut C., Lambert V., Noеl A. et al. Presence of oestrogen receptor type β in human retina // Br. J. Ophthalmol.— 2001.— Vol. 85.— P. 877-882.
37. Nathanson J.A., McKee M. Identification of an extensive system of nitrc oxide-producing cells in the ciliary muscle and outflow pathway of the human eye // Invest. Ophthalmol. Vis. Sci.— 1995.— Vol. 36.— P. 1765-1772.
38. Ogueta S.B., Schwartz S.D., Yamashita C.K., Farber D.B. Estrogen Receptor in the Human Eye: Influence of Gender and Age on Gene Expression // Invest. Opthalmol. Vis. Sci.— 1999.— Vol. 40.— Aug.— № 9.— P. 1906-1911.
39. Ozcura F., Dundar S.O., Cetin E.D. et al. Effect of estrogen replacement therapy on lens epithelial cell apoptosis in an experimental rat model // International ophthalmology.— 2010.— Vol. 30 (3).— P. 279-284.
40. Paech K., Webb P., Kuiper G.G. et al. Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites // Science.— 1997.— Vol. 277.— P. 1508-1510.
41. Pasquale L.R., Kang J.H. Female reproductive factors and primary open-angle glaucoma in the Nurses’ Health Study // Eye (Lond).— 2011.— Vol. 25.— P. 633-641.
42. Pelit A., Bagis T., Kayaselcuk F., et al. Tear function tests and conjunctival impression cytology before and after hormone replacement therapy in postmenopausal women // Eur. J. Ophthalmol.— 2003.— Vol. 13.— P. 337-342.
43. Prestwood K.M., Unson C., Kulldorff M., Cushman M. The effect of different doses of micronized 17β-estradiol on C-reactive protein, interleukin-6, and lipids in older women // J. Gerontol. A Biol. Sci. Med. Sci.— 2004.— Vol. 59.— P. 827-832.
44. Rakic J.-M., Lambert V., Deprez M. et al. Estrogens reduce the expression of YKL-40 in the retina: implications for eye and joint diseases // Invest Ophthalmol Vis Sci.— 2003.— Vol. 44 (4).— P. 1740-1746.
45. Rakoczy E.P., Zhang D., Lay M., Constable I. Accelerated rod outer segment (ROS) derived debris accumulation linked to the production of enzymatically inactive cathepsin D // Invest. Ophthalmol. Vis. Sci.— 2000.— Vol. 41.— Abstract 2190.
46. Schaumberg D.A., Buring J.E., Sullivan D.A., Dana M.R. Hormone replacement therapy and dry eye syndrome // JAMA.— 2001.— Vol. 286.— P. 2114-2119.
47. Scott G., Yiu S. C., Wasilewski D. et al. Combined esterified estrogen and methyltestosterone treatment for dry eye syndrome in postmenopausal woman // Am. J. Ophthalmol.— 2005.— Vol. 139, № 6.— P. 1109-1110.
48. Seitzman R.L., Mangione C., Ensrund K.E. et al. Postmenopausal hormone therapy and age-related maculopathy in older women // Ophthalmic Epidemiol.— 2008.— Vol. 15.— P. 308–316.
49. Siesky B.A., Harris A., Patel C. et al. Comparison of visual function and ocular hemodynamics between pre– and postmenopausal women // Eur. J. Ophthalmol.— 2008.— Vol. 18.— P. 320-323.
50. Spelsberg H., Klueppel M., Reinhard T. et al. Detection of Oestrogen receptors (ER) α and β in conjunctiva, lacrimal gland, and tarsal plates // Eye.— 2004.— Vol. 18.— P. 729-733.
51. Sullivan D.A. Androgen deficiency & dry eye syndromes // Arch. Soc. Esp. Oftalmol.— 2004.— Vol. 79.— P. 49-50.
52. Suzuki T., Kinoshita Y., Tachibana M. et al. Expression of sex steroid hormone receptors in human cornea // Curr. Eye Res.— 2001.— Vol. 22.— P. 28-33.
53. Tachibana M., Kasukabe T., Kobayashi Y. et al. Expression of estrogen receptor alpha and beta in the mouse cornea // Invest. Ophthalmol. Vis. Sci.— 2000.— Vol. 41.— P. 668-670.
54. Tint N.L., Alexander P., Tint K.M. et al. Hormone therapy and intraocular pressure in nonglaucomatous eyes // Menopause.— 2010.— Jan.-Feb.— Vol. 17 (1).— P. 157-160.
55. Uncu G., Avci R., Uncu Y. et al. The effects of different hormone replacement therapy regimens on tear function, intraocular pressure and lens opacity // Gynecol. Endocrinol.— 2006.— Vol. 22, N 9.— P. 501-505.
56. Vance D.A. Premarin: The Intriguing History of a Controversial Drug // International Journal of Pharmaceutical Compounding.— 2007.— Vol. 11 (4).— P. 282-287.
57. Wang C., Shi X., Chen X. et al. 17-β-estradiol inhibits hyperosmolarity-induced proinflammatory cytokine elevation via the p38 MAPK pathway in human corneal epithelial cells // Molecular Vision.— 2012.— Vol. 18.— P. 1115-1122.
58. Wang X., Simpkins J.W., Dykens J.A., Cammarata P.R. Oxidative damage to human lens epithelial cells in culture: Estrogen protection of mitochondrial potential, ATP, and cell viability // Invest. Ophthalmol. Vis. Sci. 2003.— Vol. 44, №5.— P. 2067-2075.
59. Wickham L. A., Gao J., Toda I. et al. Identification of androgen, estrogen and progesterone receptor mRNAs in the eye // Acta Ophthalmol. Scand.— 2000.— Vol. 78.— P. 146-153.
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