Репозиторий OAI—PMH
Репозиторий Российская Офтальмология Онлайн по протоколу OAI-PMH
Конференции
Офтальмологические конференции и симпозиумы
Видео
Видео докладов
| Реферат RUS | Реферат ENG | Литература | Полный текст |
| УДК: | 617.7-007.681 DOI: https://doi.org/10.25276/0235-4160-2025-1-103-114 |
Дога А.В., Ободова К.В.
Современные подходы к лечению больных с начальной стадией первичной открытоугольной глаукомы

НМИЦ «МНТК «Микрохирургия глаза» им. акад. С.Н. Федорова» Минздрава РФ
Екатеринбургский центр МНТК «Микрохирургия глаза»
1. Нероев В.В., Михайлова Л.А., Малишевская Т.Н., Петров С.Ю., Филиппова О.М. Эпидемиология глаукомы в Российской Федерации. Российский офтальмологический журнал. 2024;17(3): 7–12. [Neroev VV, Mikhaylova LA, Malishevskaya TN, Petrov SYu, Filippova OM. Glaucoma epidemiology in the Russian Federation. Russian Ophthalmological Journal. 2024;17(3): 7–12. (In Russ.)]
2. Куроедов А.В., Брежнев А.Ю., Ловпаче Д.Н., Петров С.Ю., Тибиева З.У., Нагорнова З.М., Криницына Е.А., Сергеева В.М. Целесообразность применения дифференцированных («ступенчатых») стартовых подходов к лечению больных с разными стадиями глаукомы. Национальный журнал Глаукома. 2018;17(4): 27–54. [Kuroedov AV, Brezhnev AYu, Lovpache JN, Petrov SYu, Tibieva ZU, Nagornova ZM, Krinitsyna EA, Sergeeva VM. The feasibility of adopting «stepwise» initial approaches in treatment of patients with different stages of glaucoma. National Journal glaucoma. 2018;17(4): 27–54. (In Russ.)]
3. Шиловских О.В., Стренёв Н.В., Пасенова И.Г. Оценка состояния диспансеризации больных глаукомой на примере крупного промышленного центра. Национальный журнал глаукома 2013;1: 24–27. [Shilovskikh OV, Strenev NV, Pasenova IG. Estimation of glaucoma patients monitoring through the example of a big industrial city. National Journal glaucoma. 2013;1: 24– 27. (In Russ.)].
4. Tsai JC. A comprehensive perspective on patient adherence to topical glaucoma therapy. Ophthalmology. 2009;116: 30–36.
5. Newman-Casey PA, Robin AL, Blachley T, et al. The most common barriers to glaucoma medication adherence: a cross-sectional survey. Ophthalmology. 2015;122(7): 1308–1316.
6. Baudouin C, Labbe A, Liang H, et al. Preservatives in eyedrops: the good, the bad and the ugly. Prog Retinal Eye Res. 2010;29(4): 312–324.
7. Ободова К.В., Стренёв Н.В. Значение анкетирования и скрининговой тонометрии для раннего выявления глаукомы. Национальный журнал глаукома. 2024;23(2): 19–25. [Obodova KV, Strenev NV. Importance of questionnaires and screening tonometry for early detection of glaucoma. National Journal glaucoma. 2024;23(2): 19–25. (In Russ.)]
8. Куроедов А.В., Абышева Л.Д., Авдеев Р.В. и др. Эффективность и затраты на местную гипотензивную терапию у пациентов с первичной открытоугольной глаукомой в странах СНГ. Проблемы здоровья и экологии. 2015;1: 28–38. [Kuroedov AV, Abysheva LD, Avdeev RV, et al. The effectiveness and costs of local antihypertensive therapy in patients with primary open-angle glaucoma in the CIS countries. Problems of health and ecology. 2015;1: 28–38. (In Russ.)]
9. Kymes SM, et al. Management of ocular hypertension: a costeffectiveness approach from the ocular Hypertension Treatment Study. Am J Ophthalmol. 2006;141(6): 997–1008.
10. Коновалова О.С., Пономарева М.Н. Коновалова Н.А. Сахаолва С.В. и др. Выборочное эпидемиологическое исследование по структуре и видам глаукомы в условиях круглосуточного офтальмологического стационара. Вестник ТГУ. 2017;4. [Konovalova OS, Ponomareva MN, Konovalova NA, Sakharova SV, et al. A selective epidemiological study on the structure and types of glaucoma in a 24-hour ophthalmological hospital. Bulletin of TSU. 2017;4. (In Russ.)]
11. Петров С.Ю., Ловпаче Д.Н., Брежнев А.Ю. Принципы приверженности лечению среди пациентов с глаукомой согласно IV изданию Европейского глаукомного руководства (аналитический комментарий). РМЖ: Клиническая офтальмология. 2015;15(3): 152–154. [Petrov SYu, Lovpache DN, Brezhnev AYu. Principles of adherence to treatment among patients with glaucoma according to the IV edition of the European Glaucoma Manual (analytical commentary). RMJ: Clinical ophthalmology. 2015;15(3): 152–154. (In Russ.)]
12. Петров С.Ю., Ловпаче Д.Н., Лоскутов И.А., Сафонова Д.М. Влияние местной гипотензивной терапии на состояние тканей переднего отрезка глаза и исход фистулизирующей хирургии глаукомы. Офтальмологические ведомости. 2017;10(4): 41–47. [Petrov SYu, Lovpache DN, Loskutov IA, Safonov DM. The effect of local hypotensive therapy on the condition of the tissues of the anterior segment of the eye and the outcome of fistulizing glaucoma surgery. Ophthalmology Reports. 2017;10(4): 41–47. (In Russ.)]
13. Fukuchi T, Wakai K, Suda K, Nakatsue T, Sawada H, Hara H, et al. Incidence, severity and factors related to drug-induced keratoepitheliopathy with glaucoma medications. Clin Ophthalmol. 2010;4: 203–209.
14. Alm A, Grierson I, Shields MB. Side effects associated with prostaglandin analog therapy. Surv Ophthalmol 2008;53: S93– 105.
15. Schwab IR, Linberg JV, Gioia VM, et al. Foreshortening of the infe rior conjunctival fornix associated with chronic glaucoma medications. Ophthalmology. 1992;99(2): 197–202.
16. Thorne JE, Anhalt GJ, Jabs DA. Mucous membrane pemphigoid and pseudopemphigoid. Ophthalmology. 2004;111(1): 45–52.
17. Sharkawi E, Franks W. Glaucoma and mortality. Ophthalmology 2008;115: 213–214.
18. Roughead EE, Kalisch LM, Pratt NL, Killer G, Barnard A, Gilbert AL. Managing glaucoma in those with co-morbidity: not as easy as it seems. Ophthalmic Epidemiol. 2012;19: 74–82.
19. Nordstrom BL, Friedman DS, Mozaffari E, Quigley HA, Walker AM. Persistence and adherence with topical glaucoma therapy. Am J Ophthalmol. 2005;140: 598–606.
20. Tsai JC. A comprehensive perspective on patient adherence to topical glaucoma therapy. Ophthalmology. 2009;116: 30–36.
21. Broadway D, Grierson I, Hitchings R. Adverse effects of topical antiglaucomatous medications on the conjunctiva. Br J Ophthalmol. 1993;77: 590–596.
22. Lama PJ, Fechtner RD. Antifibrotics and wound healing in glaucoma surgery. Surv Ophthalmol. 2003;48(3): 314–346.
23. European Glaucoma Society: Terminology and guidelines for glaucoma. 3rd edition. Savona: Italy Editrice Dogma; 2008.
24. Петров С.Ю., Ловпаче Дж.Н., Лоскутов И.А., Сафонова Д.М. Влияние местной гипотензивной терапии на состояние тканей переднего отрезка глаза и исход фистулизирующей хирургии глауком. Офтальмологические ведомости. 2017;10(4): 41–47. [Petrov SYu, Lovpache JN, Loskutov IA, Safonov DM. The effect of local hypotensive therapy on the condition of the tissues of the anterior segment of the eye and the outcome of fistulizing glaucoma surgery. Ophthalmological reports. 2017;10(4): 41–47. (In Russ.)]
25. Latina MA, Park C. Selective targeting of trabecular meshwork cells: In vitro studies of pulsed and CW laser interactions. Exp Eye Res. 1995,60: 359–371.
26. Kramer TR, Noecker RJ. Comparison of the morphologic changes after selective laser trabeculoplasty and argon laser trabeculoplasty in human eye bank eyes. Ophthalmology. 2001;108: 773–779.
27. Latina MA, Sibayan SA, Shin DH, Noecker RJ, Marcellino G. Q-switched 532-nm Nd:YAG laser trabeculoplasty (selective laser trabeculoplasty): A multicenter, pilot, clinical study11Dr. Mark A. Latina has financial interest in this technology. Ophthalmology. 1998;105: 2082–2090.
28. Аnderson RR, Parrish JA. Selective photothermolysis: Precise microsurgery by selective absorption of pulsed radiation. Science. 1983;220: 524–527.
29. Bylsma SS, Samples JR, Ascott TS, Van Buskirk M. Trabecular cell division after argon laser trabeculoplasty. Archives of Ophthalmology. 1988;106(4): 544–547.
30. Wise JB. Glaucoma treatment by trabecular tightening with the argon laser. Int Ophthalmol Clin. 1981;21(1): 69–78.
31. Bradley JM, Anderssohn AM, Colvis CM, et al. Mediation of laser trabeculoplasty-induced matrix metalloproteinase expression by IL-1beta and TNFalpha. Invest Ophthalmol Vis Sci. 2000;41(2): 422–430.
32. Cellini M, Leonetti P, Strobbe E, Campos EC. Matrix metalloproteinases and their tissue inhibitors after selective laser trabeculoplasty in pseudoexfoliative secondary glaucoma. BMC Ophthalmol. 2008;8: 20.
33. Bradley JM, Anderssohn AM, Colvis CM, Parshley DE, Zhu XH, Ruddat MS, Samples JR, Acott TS. Mediation of laser trabeculoplasty-induced matrix metalloproteinase expression by IL-1beta and TNFalpha. Investig. Ophthalmol Vis Sci. 2000;41: 422–430.
34. Parshley DE, Bradley JM, Fisk A, Hadaegh A, Samples JR, Van Buskirk EM, Acott TS. Laser trabeculoplasty induces stromelysin expression by trabecular juxtacanalicular cells. Investig Ophthalmol Vis Sci. 1996;37: 795–804.
35. Yu-Feng Chen, Wen Zeng. Mechanism of selective laser trabeculoplasty: a systemic review. Int J Ophthalmol. 2024;17(5): 963–968.
36. Latina MA, Park C. Selective targeting of trabecular meshwork cells: in vitro studies of pulsed and CW laser interactions. Exp Eye Res. 1995;60(4): 359–371.
37. Gupta M, Heo JY, Gong H, Cha E, Latina M, Rhee DJ. Morphologic and cellular changes induced by selective laser trabeculoplasty.
38. Di X, Fan X, Zhou J, Wu L. Effectiveness of unilateral selective laser trabeculoplasty for primary open angle glaucoma. Chinese J Ophthalmol. 2016;52: 410–415.
39. Garg A, Gazzard G. Selective laser trabeculoplasty: Past, present, and future review-article. Eye. 2018;32: 863–876. doi: 10.1038/ eye.2017.273
40. Пасенова И.Г., Алексеева К.В. Анализ эффективности селективной лазерной трабекулопластики. Сибирский научный медицинский журнал. 2019;39(3): 39–44. [Pasenova IG, Alekseeva KV. Analysis of the effectiveness of selective laser trabeculoplasty. Siberian Scientific Medical Journal. 2019;39(3): 39–44. (In Russ.)]
41. Gracner T, Falez M, Gracner B, Pahor D. Long-term follow-up of selective laser trabeculoplasty in primary open-angle glaucoma. Klin Monatsbl Augenheilkd. 2006;223(9): 743–747.
42. Koucheki B, Hashemi H. Selective laser trabeculoplasty in the treatment of openangle glaucoma. J Glaucoma. 2012;21(1): 65– 70. doi: 10.1097/IJG.0b013e3182027596
43. Weinand FS, Althen F. Long-term clinical results of selective laser trabeculoplasty in the treatment of primary open-angle glaucoma. Eur J Ophthalmol. 2006;16(1): 100–104.
44. Latina MA, Sibayan SA, Shin DH, Noecker RJ, Marcellino G. Q-switched 532-nm Nd:YAG laser trabeculoplasty (selective laser trabeculoplasty): A multicenter, pilot, clinical study Ophthalmology. 1998;105: 2082–2088.
45. Song J, Lee PP, Epstein DL, Stinnett SS, Herndon LW Jr, Asrani SG, et al. High failure rate associated with 180 degrees selective laser trabeculoplasty. J Glaucoma. 2005;14: 400–408.
46. Michaelov E, Sachdeva R, Raniga A, Lin T. A randomized, controlled comparison of 180 versus 360 degrees selective laser trabeculoplasty in open angle glaucoma and glaucoma suspects. J Glaucoma. 2023;32: 252–256.
47. Shibata M, Sugiyama T, Ishida O, Ueki M, Kojima S, Okuda T, et al. Clinical results of selective laser trabeculoplasty in open-angle glaucoma in Japanese eyes: Comparison of 180 degree with 360 degree SLT. J Glaucoma. 2012;21: 17–21.
48. Nirappel A, Klug E, Ye R, Hall N, Chachanidze M, Chang TC, et al. Effectiveness of selective laser trabeculoplasty applied to 360° vs. 180° of the angle. J Ophthalmol. 2021: 8860601. doi: 10.1155/2021/8860601
49. Prasad N, Murthy S, Dagianis JJ, Latina MA. A comparison of the intervisit intraocular pressure fluctuation after 180 and 360 degrees of selective laser trabeculoplasty (SLT) as a primary therapy in primary open angle glaucoma and ocular hypertension. J Glaucoma. 2009;18: 157–160.
50. Tawfique K, Khademi P, Querat L. Comparison between 90degree and 360degree selective lasertrabeculoplasty (SLT): A 2year followup. Acta Ophthalmol. 2019;97(4): 427–429.
51. Paula JS, Senger C, Moraes CG. Comparison of the short-term results of nasal and temporal 180° selective laser trabeculoplasties for open-angle glaucoma. Arq Bras Oftalmol. 2023;86: 217–222.
52. Goyal S, Beltran-Agullo L, Rashid S, Shah SP, Nath R, Obi A, et al. Effect of primary selective laser trabeculoplasty on tonographic outflow facility: A randomised clinical trial. Br J Ophthalmol. 2010;94: 1443–1447.
53. Chen E, Golchin S, Blomdahl S. A comparison between 90 degrees and 180 degrees selective laser trabeculoplasty. J Glaucoma. 2004;13(1): 62–65.
54. Nagar M, Ogunyomade A, O’Brart DP. A randomised, prospective study com paring selective laser trabeculoplasty with latanoprost for the control of intraocular pressure in ocular hypertension and open angle glaucoma. Br J Ophthalmol. 2005;89(11): 1413–1417.
55. Wong C, Tao LW, Skalisky SE. A retrospective review comparing the safety and efficacy of 120 versus 160 applications of selective laser trabeculoplasty. J Glaucoma. 2018;27(1): 94–99.
56. Zhang HY, Qin YJ, Yang YF, Xu JG, Yu MB. Intraocular pressurelowering potential of subthreshold selective laser trabeculoplasty in patients with primary open-angle glaucoma. J Ophthalmol. 2016;2016: 2153723.
57. Gandolfi SA, Ungaro N, Varano L, Saccà S. Low power selective laser trabeculoplasty (SLT) repeated yearly as primary treatment in open angle glaucoma(s): Long term comparison with conventional SLT and ALT. Investig Ophthalmol Vis Sci. 2018;59: 3459.
58. Gandolfi SA, Ungaro N. Low power selective laser trabeculoplasty (SLT) repeated yearly as primary treatment in ocular hypertension: long term comparison with conventional SLT and Alt. Invest Ophthalmol Vis Sci. 2014;55: 818.
59. Jian GE, Sun X, Ding L, et al. Multicenter clinical study of safety and efficacy of selective laser trabeculoplasty for Chinese primary open angle glaucoma. Chin J Exp Ophthalmol. 2014;32: 159–162.
60. Xu L, Yu RJ, Ding XM, et al. Efficacy of low-energy selective laser trabeculoplasty on the treatment of primary open angle glaucoma. Int J Ophthalmol. 2019;12: 1432–1437.
61. Latina MA, Park C. Selective targeting of trabecular meshwork cells: in vitro studies of pulsed and CW laser interactions. Exp Eye Res. 1995;60(4): 359–371.
62. Izzotti A, Longobardi M, Cartiglia C, Rathschuler F, Saccà SC. Trabecular meshwork gene expression after selective laser trabeculoplasty. PLoS One. 2011;6(7): e20110.
63. SooHoo JR, Seibold LK, Ammar DA, Kahook MY. Ultrastructural changes in human trabecular meshwork tissue after laser trabeculoplasty. J Ophthalmol. 2015; 476138.
64. Cvenkel B, Hvala A, Drnovšek-Olup B, Gale NN. Acute ultrastructural changes of the trabecular meshwork after selective laser trabeculoplasty and low power argon laser trabeculoplasty. Lasers Surg Med. 2003;33(3): 204–208.
65. Baser EF, Akbulut D. Significant peripheral anterior synechiae after repeat selective laser trabeculoplasty. Can J Ophthalmol. 2015;50(3): e36–38.
66. Latina MA, Sibayan S, Dong H, et al. Q-switched532-nm Nd:YAG laser trabeculoplasty (selective laser trabeculoplasty). Ophthalmology. 1998;105(11): 2082–2090.
67. Damji KF, Shah KC, Rock WJ. Selective laser trabeculoplasty. Br J Ophthailmol. 1999;83: 718–722.
68. Lai JS, Chua JK, Tham CC, Lam DS. Five-year follow up of selective laser trabeculoplasty in Chinese eyes. Clin Exp Ophthalmol. 2004;32: 368–372.
69. Rhee DJ, Krad O, Pasquale LR. Hyphema following selective laser trabeculoplasty. Ophthalmic Surg Lasers Imaging. 2009;40(5): 493–494.
70. Shinden W, Ritch R, Liebman J. Hyphema occurung during selective laser trabeculoplasty. Ophthalmic Surg. Lasers Imaging. 2006;37(5): 432–433.
71. Meredith R, Bunya V, Orlin S. Corneal edema and haze after selective laser trabeculoplasty. J Glaucoma. 2011;20(5): 327–329.
72. Moubayed S, Hamid M, Choremis J, Li G. An unusual findings of corneal edema complicating selective laser trabeculoplasty. Can J Ophthalmol. 2009;44(3): 337–338.
73. Ong K, Ong L, Ong L. Corneal endothelial changes after selective laser tra_beculoplasty. Clinical and Experimental Ophthalmology. 2013;41(6):537–540.
74. Alvarado JA, Chau P, Wu J, Juster R, Shifera AS, Geske M. Profiling of cytokines secreted by conventional aqueous outflow pathway endothelial cells activated in vitro and ex vivo with laser irradiation. Invest Ophthalmol Vis Sci. 2015;56: 7100.
75. Guzey M, Vural H, Satici A, Karadede S, Dogan Z. Increase of free oxygen radicals in aqueous humour induced by selective Nd:YAG laser trabeculoplasty in the rabbit. Eur J Ophthalmol. 2001;11: 47–52.
76. White AJ, Mukherjee A, Hanspal I, Sarkies NJ, Martin KR, Shah P. Acute transient corneal endothelial changes following selective laser trabeculoplasty. Clin Exp Ophthalmol. 2013;41: 435–441.
77. Paiva ACM, da Fonseca AS. Could adverse effects and complications of selective laser trabeculoplasty be decreased by low-power laser therapy? Int Ophthalmol. 2019;39: 243–257.
78. Realini T, Gazzard G, Latina M, et al. Low-energy selective laser trabeculoplasty repeated annually: rationale for the COAST trial. J Glaucoma. 2021;30: 545–551.
79. Lee JWY, Chan JCH, Chang RT, et al. Corneal changes after a single session of selective laser trabeculoplasty for open-angle glaucoma. Eye (Lond). 2014;28: 47–52.
80. Gazzard G, Konstantakopoulou E, Garway-Heath D, Garg A, Vickerstaff V, Hunter R, Ambler G, Bunce C, Wormald R, Nathwani N, et al. Selective laser trabeculoplasty versus eye drops for firstline treatment of ocular hypertension and glaucoma (LiGHT): A multicentre randomised controlled trial. Lancet. 2019;393: 1505–1516.
81. Garg A, Vickerstaff V, Nathwani N, Garway-Heath D, Konstantakopoulou E, Ambler G, Bunce C, Wormald R, Barton K, Gazzard G, et al. Primary selective laser trabeculoplasty for open-angle glaucoma and ocular hypertension: Clinical outcomes, predictors of success, and safety from the laser in glaucoma and ocular hypertension trial. Ophthalmology. 2019;126: 1238–1248.
82. Garg A, Vickerstaff V, Nathwani N, Garway-Heath D, Konstantakopoulou E, Ambler G, Bunce C, Wormald R, Barton K, Gazzard G. Efficacy of repeat selective laser trabeculoplasty in medication-naive open-angle glaucoma and ocular hypertension during the LiGHT trial. Ophthalmology. 2020;127: 467–476.
83. Kiddee W, Atthavuttisilp S. The effects of selective laser trabeculoplasty and travoprost on circadian intraocular pressure fluctuations. Medicine. 2017; 96.
84. Ansari E. 10-year outcomes of first-line selective laser trabeculoplasty (SLT) for primary open-angle glaucoma (POAG). Graefes Arch Clin Exp Ophthalmol. 2021;259(6): 1597–1604. doi: 10.1007/s00417-021-05098-z
85. Stapleton F, Alves M, Bunya VY, Jalbert I, Lekhanont K, Malet F, Na K-S, Schaumberg D, Uchino M, Vehof J, et al. TFOS DEWS II Epidemiology. Report Ocul Surf. 2017;15: 334–365.
86. Filippopoulos T, Paula JS, Torun N, Hatton MP, Pasquale LR, Grosskreutz CL. Periorbital changes associated with topical bimatoprost. Ophthalmic Plast Reconstr Surg. 2008;24(4): 302– 307.
87. Germano RAS, Hatanaka M, Garcia AS. Comparison of the hypotensor effect between latanoprost versus selective laser trabeculoplasty obtained with the water drinking test. Arq Bras Oftalmol. 2021;84: 361–366.
88. Селезнев А.В. Характеристика гипотензивной эффективности селективной лазерной трабекулопластики при первичной открытоугольной глаукоме. Вестник Ивановской медицинской академии. 2014;9(4): 83. [Seleznev AV. Characteristics of the hypotensive effectiveness of selective laser trabeculoplasty in primary open-angle glaucoma. Bulletin of the Ivanovo Medical Academy. 2014;9(4): 83. (In Russ.)]
89. Анисимова С.Ю., Анисимов С.И., Кочмала О.Б. и др. Сравнительные Результаты местного и лазерного лечения вновь выявленных больных первичной глаукомой. Национальный журнал глаукома. 2024;23(3): 37–43. [Anisimova SYu, Anisimov SI, Kochmala OB, et al. Comparative results of local and laser treatment of newly diagnosed patients with primary glaucoma. National Journal of Glaucoma. 2024;23(3): 37–43. (In Russ.)]
90. Патент РФ на изобретение № 2024113910/22.05.2024. Бюл. № 20. Ободова К.В., Стренев Н.В. Способ комбинированного лазерного лечения первичной открытоугольной глаукомы при наличии пигментации структур угла передней камеры. Доступно по: https://patents.google.com/ patent/RU2822962C1/ru [Ссылка на 23.01.2025] [Patent RUS № 2024113910/22.05.2024. Byul. № 20. Obodova KV, Strenev NV. A method of combined laser treatment of primary openangle glaucoma in the presence of pigmentation of the anterior chamber angle structures. Available from: https://patents.google. com/patent/RU2822962C1/ru [Accessed 23rd January 2025] (In Russ.)]
Страница источника: 103
Каталог
Продукции
Организации
Офтальмологические клиники, производители и поставщики оборудования
Издания
Периодические издания
Партнеры
Проекта Российская Офтальмология Онлайн
С Новым годом!



















