Analysis of the effectiveness of complex treatment of exudative form of age-related macular dystrophy

    Abstract

    A-G.D. Aliev, A.A-G. Aliev, S.I. Zakieva, M.M. Mikailova, M.M. Magomedova

    Analysis of the effectiveness of complex treatment of exudative form of age-related macular dystrophy

    State Budgetary Institution “Dagestan Center of Eye Microsurgery”, Kaspiysk

    Purpose. Evaluation of the effectiveness of complex treatment of exudative form of age-related macular dystrophy.

    Material and methods. We studied 32 patients with exudative form of age-related macular dystrophy, which were divided into 2 groups. Patients of the 1st group received intravitreal inhibitor of neoangiogenesis ranibizumab (0,5 mg). Patients of the 2nd group received a combined treatment, consisting of two stages: subtenon injection of prolonged corticosteroid Diprospan in the volume of 0.5 ml, combined with subsequent (after 15-20 days) intravitreal injection of ranibizumab in the volume of 0,5mg.

    Results. In both groups, the maximum therapeutic effect was observed in the periods from 2 weeks till 3 months. In future (after 6-12 months) only in the 2nd group, receiving a complex treatment, the visual acuity was significantly higher than the initial data, which indicates the stability of the achieved results.

    Conclusions. Complex therapy of exudative form of age-related macular dystrophy with the use of corticosteroid Diprospan and inhibitor of neoangiogenesis Ranibizumab leads to a sustained improvement of visual acuity, rapid and stable decrease of edema in macular area and reduction of the risk of progression of dystrophic processes in the retina.

    Key words: age-related macular dystrophy, macular edema, treatment, corticosteroids, inhibitors of neoangiogenesis.