Frequency and character of general somatic diseases associated with the different types of senile cataract formation in human

Purpose

To investigate the influence of dominating part of vegetative nervous system and to provide comparative analysis of general somatic pathology associated with the different types of senile cataract formation in human.


Material and methods

The retrospective analysis of case reports of 198 patients over 60 years old who attended the outpatients department between December 2004 and August 2009 has been carried out in blind statistical analysis design. On the basis of biomicroscopic investigation, two groups of patients with different types of native lens opacification were formed: group A: 92 patients with senile cortical layers opacity; group B: 157 patients with senile nuclear opacity. Different methods of general therapeutic investigations were used during the patients follow-up.


Results

Analysis of frequency and character of general somatic diseases associated with the senile cataract formation in human demonstrates the appropriate manifestations of vegetative nervous system involution. Therefore, it is assumed that there is a strong pathogenic correlation between type of semile lens opacity and general somatic status. Achieved data confirmed the necessity of a differential approach to investigation of noted pathogenic mechanisms and the possibility of using the type of opacity as the marker of general pathology. It is a helpful tool for ophthalmic surgeon to predict different complications in early pre- and post-operative period in treatment of specific cataract type.


Conclusion

Thus, the domination а sympathetic nervous system and correlated systemic dystrophic changes of the tissues in patients with cortical cataract is found for the first time. Moreover, in patients with nuclear cataract the domination of parasympathetic nervous system is revealed initiating another character of dystrophic changes.


Key words

lens, senile cataract, pathogenesis, vegetative nervous system