Study of Surgically Formed Drain Pathwaysin Combined Neovascular Glaucoma Treatment

    Abstract

    Study of Surgically Formed Drain Pathwaysin Combined Neovascular Glaucoma Treatment

    E.N. Bilalov, S.Sh. Mirrakhimova, K.I. Narzikulova, B.E. Bilalov

    Tashkent Medical Academy, Tashkent (Uzbekistan)

    Purpose – to conduct a comparative analysis of surgically formed drain pathways based on eye ultrasonic biomicroscopy after neovascular glaucoma (NVG) combined treatment involving photodynamic therapy.

    Material and methods. 91 NVG patients (91 eyes) divided into 3 groups were treated: the 1st (control group) – 32 patients (32 eyes)who underwent glaucoma surgeries (GS) when instilling hypotensive drops; the 2nd one – 30 patients (30 eyes) who canceled all hypotensive drops 6 days prior to the surgery and instilled Brimoptic 5 days prior to the surgery; the 3rd group – 29 patients (29 eyes) who instilled Brimoptic before and after the surgery and received photodynamic therapy with a machine.

    Results. The group 2 patients with stage III NVG had their IOP compensated in 60% of cases, those in group 3 – in 71%, in the control group – 25%. After 6 months the tonometric IOP of the group 2 patients was 23.8±1.2 mm Hg on the average, that in group 3 – 21.9±1.5 and 22.1±1.4 mm Hg for NVG stages II and III respectively.

    Conclusion.These findings show the effectiveness of the developed treatment involving Brimoptic in the preoperative preparation and photodynamic therapy after the NVG surgery. Imaging of the fluid outflow pathways after the GS involving PDT studied with ultrasonic biomicroscopy indicates that the filtering bleb parameters are stable and the lumen of the intrascleral cavity is preserved (in 75% of cases) ensuring patency of the drain pathways formed during the NVG.

    Key words: neovascular glaucoma, laser therapy, photodynamic therapy.