Simultaneous sinustrabeculectomy and laser cyclocoagulation in the treatment of refractory glaucoma

    Abstract

    Original article

    Simultaneous sinustrabeculectomy and laser cyclocoagulation in the treatment of refractory glaucoma

    S.Kh. Kholmatov, H.D. Karim-Zadeh, S.K. Makhmadzoda, S.M. Mirzoev

    Department of Ophthalmology of the Avicenna Tajik Medical University, Dushanbe, Republic of Tajikistan
Institute of Healthcare Postgraduate Education of the Republic of Tajikistan, Dushanbe, Republic of Tajikistan

    Purpose. To evaluate the efficacy and safety of simultaneous trabeculectomy (TE) and micropulse cyclocoagulation (mLCC) in patients with refractory glaucoma.

    Material and methods. A preliminary analysis of the results of the efficacy and safety of TE (26 eyes) and TE with simultaneous mLCC (26 eyes) in refractory glaucoma with a follow-up period of 12 months was carried out.

    Results. After TE, the average IOP in the group decreased from 40.52±0.34 mmHg before surgery to 25.1±0.3 mmHg after 12 months (by 38.1%); after TE with simultaneous mLCC — from 38.12±4.8 mmHg to 17.3±2.1 mmHg (by 54.6%). After TE, the use of medicines decreased on average from 2.7±1.2 to 1.7±0.5, and after TE with simultaneous mLCC — from 2.8±1.4 to 0.75±0.2. After combined surgical treatment, a decrease in IOP of more than 20% compared to the baseline level was recorded at 65.4%, and a decrease in IOP to a level of less than 15 mmHg. in 53.8%, and in the control group in 53.8% and 46.6%, respectively. At the same time, performing mLCC simultaneously with TE can significantly reduce the risk of developing transient hypotension in the early postoperative period (from 42.3% in the control group to 23.1% in the experimental group).

    Conclusion. Simultaneous administration of TE and mLCC leads to a significant decrease in IOP and a decrease in the number of complications in the postoperative period. For final conclusions about the efficacy and safety of our method of surgical treatment of glaucoma, it is necessary to conduct a prospective controlled trial based on more clinical material.

    Keywords: glaucoma, laser cyclocoagulation, micropulse mode, intraocular pressure

    For citation: Kholmatov S.Kh., Karim-Zadeh H.D., Makhmadzoda S.K., Mirzoev S.M., Simultaneous sinustrabeculectomy and laser cyclocoagulation in the treatment of refractory glaucoma Rossiyskaya detskaya oftalmologiya. 2026;1(55): 5–11.

    DOI: 10.25276/2307-6658- 2026-1-5-11

    Corresponding author: Saidjafar Kh. Kholmatov, kholmatovs@mail.ru