Ophthalmological manifestations of pharmacotherapy: substituent hormonal therapy in women

    Ophthalmological manifestations of pharmacotherapy: substituent hormonal therapy in women

    Obrubov A.S.1, Obrubov S.A.2

    1 The Chair for Ophthalmology of the Advanced Training Faculty for Physicians, the N.I. Pirogov Russian National Research Medical University, Moscow;
2 The Chair for Ophthalmology of the Pediatric Faculty, the N.I. Pirogov Russian National Research Medical University, Moscow

    

    There is discussed in the article an impact of substituent hormonal therapy on a development of eye diseases in female patients in peri– and post-menopause. A distribution of receptors to estrogens in ocular tissue is presented and possible mechanisms of estrogen impact on development and prevention of glaucoma, dry eye syndrome, age-related macular degeneration and cataract.

    Key words: substituent hormonal therapy, estrogenic receptors, cataract, glaucoma, dry eye syndrome, age-related macular degeneration.