Assessment using Cytoflavin® in patients after endovitreal surgery for rhegmatogenous retinal detachment complicated by proliferative vitreoretinopathy

    Purpose. To assess the functional efficiency of the obtained results of endovitreal surgery in patients with rhegmatogenous retinal detachment (RRD) by using Cytoflavin in the postoperative rehabilitation.

    Material and methods. 108 people (108 eyes) after surgery for RRD. Patients were divided into 2 groups: the 1st – 60 people who received Cytoflavin on the background of standard therapy, and the 2nd – 48 people with postoperative treatment only with standard therapy.

    We used Laser Doppler fluometry (LDF): microcirculation index and microcirculation efficiency index were recorded. Using OCT angiography (OCT-A) area nonperfusion of foveal avascular zone, density in the superficial capillary plexuses and density in the deep capillary plexuses in the macular area were investigated.

    Results. The inclusion of Cytoflavin in the postoperative rehabilitation of patients with RRD increases the possibility of a favorable functional outcome of the operation, affects the positive dynamics in the state of the capillary plexus in the macula. In the aggregate of patients of the 1st group, the increase in visual acuity was 2 times higher than in patients of the 2nd group 6 months after surgery.

    Conclusion. The prescription of Cytoflavin in the postoperative treatment of patients underwent endovitreal surgery of RRD increases the functional outcome of the operation.

    Keywords: rhegmatogenous retinal detachment, chorioretinal microcirculation, Laser Doppler fluometry, optical coherence tomography angiography, Cytoflavin.