A comparative analysis of intraocular pressure and central corneal thickness dynamics after cataract phacoemulsification with intraocular lens implantation depending on the presence of primary open-angle glaucoma

    Abstract

    A comparative analysis of intraocular pressure and central corneal thickness dynamics after cataract phacoemulsification with intraocular lens implantation depending on the presence of primary open-angle glaucoma

    Kharlamova M.S., Ekgardt V.F., Khokhlova D.Yu., Pevgov D.G., Butorina O.I.

    GAUZ City Clinical Hospital No. 1, Chelyabinsk

    South Ural State Medical University, Chelyabinsk

    GAUZ City Clinical Hospital No. 11, Chelyabinsk

    A prospective open study of 64 eyes (64 patients) was conducted, the parameters of IOP and central corneal thickness (CCT) in the early postoperative period were studied in patients with primary-open-angle glaucoma (POAG) and without glaucoma.

    The terms of normalization of these parameters are determined, as well as possible influencing factors on changes in IOP and CCT indicators. In patients with POAG after phaco an increase in hypotensive drops was required in 50 % of cases, in 19 % of patients with an average IOP after surgery up to 28.8 ± 5.2 mm Hg (p<0.01), there was a need for antiglaucoma operation (AGO) in the early postoperative period due to persistent IOP decompensation. Basically, these were patients who received 2 or 3 hypotensive drugs before phaco, had 3rd degree lens density, stage 3 glaucoma and a longer operation time. In patients without POAG an increase of IOP level is possible at day 1 after phaco to an average of 22.4±5.6 mm Hg (p=0.03), but to a lesser extent than in patients with POAG (p<0.05). This group consisted exclusively of patients with 2nd and 3rd degree of lens density and longer operation time. In patients with POAG at the day after phaco CCT index significantly increases to an average of 617.9 ±88.6 microns (p<0.001), approaching the norm at day 14. In patients without glaucoma the level of CCT at the day after surgery also equally significantly increases to an average of 624±106.3 microns, approaching the baseline level by day 14.

    Key words: early postoperative period; open-angle glaucoma; cataract; intraocular pressure; central corneal thickness.