VEGF-dependent аnti-angiogenic therapy in ophthalmology

The article is a review of literature with an analysis of contemporary аnti-angiogenic medicines, which found a clinical application in the ophthalmologists’ practice in treatment of ocular diseases, progressing with neovascularization.

The main approaches to contemporary аnti-angiogenic therapy are implemented, as well as the advantages and negative sides of medicines, their clinical effectiveness, spectrum of complications, which you can come across in practice according to the results of numerous clinical trials conducted in Europe, USA and Canada.


Key words

anti-angiogenic therapy, neovascular eye diseases, age-related macular degeneration, VEGF and VEGFR1 receptors.